A new article was published in CPT: Pharmacometrics & Systems Pharmacology

Victor Sokolov, Tatiana Yakovleva, Leonid Stolbov, Robert C. Penland, David Boulton, Joanna Parkinson, Weifeng Tang. A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes. CPT Pharmacometrics & System Pharmacology. doi: 10.1002/psp4.12956

In this work, previously developed mechanistic mathematical platform of type 2 diabetes [Shah et al. 2020] was modified to describe type 1 diabetes condition and applied to evaluate and optimize combination treatment of dapagliflozin and exogenous insulins based on the short-term and long-term changes in glycemic control.