01/10/2020
Veronika Voronova et al.
Front Oncol. 2020; 10: 832
•Diagnostic performance of 20 blood-based cancer-related 20 biomarkers was evaluated using the data from 203 healthy subjects and 102 patients with colon cancer.
•Cancer patients were characterized by multiple abnormalities in biomarker levels; diagnostic performance, evaluated via ROC analysis, varied across considered biomarkers (0.52<ROC AUC<0.90)
•Combinatorial biomarkers, exploiting several classification algorithms to predict patient status based on levels of multiple biomarkers and patient’s characteristics, were developed
• Combinatorial biomarkers demonstrated higher diagnostic performance over single-protein biomarkers
Please, see a more detailed presentation (Voronova_ColRecCar.pdf) and a full text article (fonc-10-00832.pdf)
