A new article about QSP modeling was published in Diabetes, Obesity and Metabolism

Voronova V, Zhudenkov K, Penland RC, Boulton DW, Helmlinger G, Peskov K. Exenatide effects on gastric emptying rate and the glucose rate of appearance in plasma: A quantitative assessment using an integrative systems pharmacology model. Diabetes Obes Metab. 2018; 1–5.

A QSP model was used to show that gastric emptying inhibition by exenatide represents an important additional mechanism of postprandial glucose stabilization. The drug effect depends on the food properties, which underscores the importance of dietary counseling as an adjunct to medication.